NENAD M. KOSTIĆ

Professor of Chemistry Department
Bioinorganic, Biophysical, and Bioorganic Chemistry

PUBLICATIONS

 

1. N. M. Kostić and S. R. Niketić,
"Novel Mixed Tris­complexes of Cobalt(III) with a­ and b-Amino­acids: Isolation,Adsorption Chromatography, and Absorption Spectra,"
J. Chem. Soc., Chem. Commun. 1977, 676­678.

2. N. M. Kostić and R. F. Fenske,
"Molecular Orbital Calculations on Carbyne Complexes CpMn(CO)2CR+ and (CO)5CrCNEt2+. Frontier­Controlled Nucleophilic Addition to Metal­Carbon Triple Bond,"
J. Am. Chem. Soc. 1981, 103, 4677­4685.

3. N. M. Kostić and R. F. Fenske,
"Molecular Orbital Calculations on Octahedral Carbyne Complexes: Bonding, Structure Deformations, and Frontier­Controlled Nucleophilic Additions,"
Organometallics 1982, 1, 489­496.

4. N. M. Kostić and R. F. Fenske,
"Criteria of Maximum Overlap and Minimum Orbital Energy in Molecular Orbital Studies of Conformations of Transition­Metal Carbene and Carbyne Complexes,"
J. Am. Chem. Soc. 1982, 104, 3879­3884.

5. N. M. Kostić and R. F. Fenske,
"Molecular Orbital Study of Bonding and Conformations in Dinuclear Complexes of Manganese and Chromium Containing Germanium, Sulfide, Dinitrogen or Phosphinidene Bridges,"
J. Organomet. Chem. 1982, 233, 337­351.

6. N. M. Kostić and R. F. Fenske,
"Molecular Orbital Studies of Bonding, Conformations, and Reactivity of Transition­Metal Complexes Containing Unsaturated Organic Ligands. Electrophilic and Nucleophilic Additions to Acetylide, Vinylidene, Vinyl, and Carbene Ligands,"
Organometallics 1982, 1, 974­982.

7. N. M. Kostić and R. F. Fenske,
"Xa­SW Study of Bonding, Photoelectron Spectra and Photoionization Transition States in (Cyclobutadiene)iron Tricarbonyl,"
Chem. Phys. Lett. 1982, 90, 306­309.

8. N. M. Kostić,s
"Phosphorus­Containing Analogues of Hydrocarbon Ligands. Molecular Orbital Study of Structure and Bonding in Potential Transition­Metal Complexes Containing Phosphoranium Ions as π Ligands,"
J. Organomet. Chem. 1982, 240, 71­81.

9. N. M. Kostić and R. F. Fenske,
"Molecular Orbital Study of Dinuclear Palladium Carbonyl Chlorides. Choice of the Bridging Ligand (CO versus Cl) and Question of Metal­Metal Bonding," Inorg. Chem. 1983, 22, 666­671.

10. N. M. Kostić and R. F. Fenske,
"Bonding in Phosphaferrocenes and Reactivity of the Phospholyl Ligand Studied by Molecular Orbital Calculations,"
Organometallics 1983, 2, 1008­1013.

11. N. M. Kostić and R. F. Fenske,
"Molecular Orbital Study of Bonding, Structure, and Substitution Reactions of Bis(borabenzene)iron,"
Organometallics 1983, 2, 1319­1325.

12. G. C. Hancock, N. M. Kostić, and R. F. Fenske,
"Molecular Orbital Studies of Bonding, Photoelectron Spectra, and Photoionization Transition States of Bis(π­allyl)nickel,"
Organometallics 1983, 2, 1089­1098.

13. N. M. Kostić, R. Margalit, C.­M. Che, and H. B. Gray,
"Kinetics of Long­Distance Ruthenium­to­Copper Electron Transfer in Pentaammineruthenium(histidine­83)azurin,"
J. Am. Chem. Soc. 1983, 105, 7765­7767.

14. R. Margalit, N. M. Kostić, C.­M. Che, H.­j. Chiang, I. Pecht, J. B. Shelton, J. R. Shelton, W. A. Schroeder, and H. B. Gray,
"Preparation and Characterization of Pentaammineruthenium(histidine­83) azurin and Thermodynamics of Intramolecular Electron Transfer,"
Proc. Nat. Acad. Sci. USA 1984, 81, 6554­6558.

15. N. M. Kostić,
"Organometallics - Workhorses of Chemistry,"
Encyclopedia Britannica, Yearbook of Science and the Future 1990, 146-159.
A feature article, solicited by the editor.

16. N. M. Kostić,
"Electron-Transfer Reactions of Metalloproteins,"
ACS Bioinorganic Subdivision newsletter, spring 1992.
A selective review, solicited by the editor, of research presented at the Fifth International Conference on Bioinorganic Chemistry, Oxford, Great Britain, 1991.

17. N. M. Kostić
"Kinetics and Mechanism of a Co(III) Complex Catalyzed Hydration of Nitriles,"
Commentary on J. H. Kim, J. Britten, and J. Chin, J. Am. Chem. Soc. 1993, 115, 3618;
Chemtracts-Inorganic Chemistry 1993, 5, 238-242.

18. N. M. Kostić
"The Introduction of a Negative Charge into the Hydrophobic Patch of Pseudomonas aeruginosa Azurin Affects the Electron Self-Exchange Rate and the Electrochemistry",
Commentary on G. van Pouderoyen, S. Mazumdar, N. I. Hunt, H. A. O. Hill, and G. W. Canters, Eur. J. Biochem. 1994, 222, 583;
Chemtracts-Inorganic Chemistry 1994, 6, 110-113.

19. M. M. Ivković and N. M. Kostić
"Stern-Volmer in Reverse: 2:1 Stoichiometry of the Cytochrome c-Cytochrome c Peroxidase Electron-Transfer Complex,"
Commentary on J. S. Zhou and B. M. Hoffman, Science 1994, 265, 1693; Chemtracts­Inorganic Chemistry 1995, 7, 27-32.

20. C. Shen and N. M. Kostić
"Identification of Conformational Substates in Oxymyoglobin Through the pH Dependence of the Low-Temperature Photoproduct Yield,"
Commentary on L. M. Miller, M. Patel, and M. R. Chance, J. Am. Chem. Soc. 1996, 118, 4511;
Chemtracts-Inorganic Chemistry 1997, 10, 584-587.

21. G. B. Karet and N. M. Kostić
"One- and Two-Metal Ion Catalysis of the Hydrolysis of Adenosine 3'-Alkyl Phosphate Esters. Models for One- and Two-Metal Ion Catalysis of RNA Hydrolysis,"
Commentary on T. C. Bruice, A. Tsubouchi, R. O. Dempcy, and L. P. Olson, J. Am. Chem. Soc. 1996, 118, 9867;
Chemtracts-Inorganic Chemistry 1997, 10, 138-143.

22. N. M. Kostic´ ,
“Synthesis and Structure of Formally Hexavalent Palladium Complexes”; Hexakis(silyl)palladium(VI) or Palladium(II) with h2-Disilane Ligands?”; “Electronic Structure and Bonding in Hexacoordinate Silyl-Palladium Complexes”,
Commentary on W. Chen, S. Shimada, and M. Tanaka, Science 2002, 295, 308; G. Aullón, A. Lledós, and S. Alvarez, Agnew. Chem. Int. Ed. 2002, 41, 1956; E.C. Sherer, C.R. Kinsinger, B.L. Kormos, J.D. Thompson, and C.J. Cramer, Angew. Chem. Int. Ed. 2002, 41, 1953,
Chemtracts-Inorganic Chemistry 2003, 16, 42-47.

23. D. D. Gummin, E. M. A. Ratilla, and N. M.
"Variable-Temperature 195Pt NMR Spectroscopy, A New Technique for the Study of Stereodynamics. Sulfur Inversion in a Platinum(II) Complex with Methionine,"
Inorg. Chem. 1986, 25, 2429-2433.

24. E. M. A. Ratilla, H. M. Brothers II, and N. M.
"A Transition-Metal Chromophore as a New, Sensitive Spectroscopic Tag for Proteins. Selective Labeling of Histidine Residues in Cytochromes c with Chloro(2,2':6',2"-terpyridine) Platinum(II) Chloride,"
J. Am. Chem. Soc. 1987, 109, 4592-4599.

25. L. Zhu and N. M. Kostić
"Molecular Orbital Study of Stereoselective Addition of Ligands to the Hydride, Alkyl, and Halide Complexes of Iridium and Zirconium. The Question of Central Versus Lateral Attack,"
J. Organomet. Chem. 1987, 335, 395-411.

26. J. A. Galbraith, K. A. Menzel, E. M. A. Ratilla, and N. M.Kostić
"Study of Stereodynamics by Variable-Temperature l95Pt NMR Spectroscopy. Diastereomerism in Platinum(II) Thioether Complexes and Solvent Effects,"
Inorg. Chem. 1987, 26, 2073-2078.

27. L. M. Peerey and N. M.Kostić
"Transition-Metal Compounds as New Reagents for Selective Cross-Linking of Proteins. Synthesis and Characterization of Two Bis(cytochrome c) Complexes of Platinum,"
Inorg. Chem. 1987, 26, 2079-2083.

28. L. Zhu and N. M.Kostić
"Molecular Orbital Study of Coenzyme B12 Activation of the Cobalt-Carbon Bond by Angular Distortions,"
Inorg. Chem. 1987, 26, 4194-4197.

29. H. M. Brothers II and N. M. Kostić
"Noninvasive Tagging of Proteins with an Inorganic Chromophore. Selectivity of Chloro(2,2':6',2"-terpyridine)platinum(II) Toward Amino Acids, Peptides, and Cytochromes c,"
Inorg. Chem. 1988, 27, 1761-1767.

30. L. Zhu and N. M. Kostić
"Molecular Orbital Study of Bimetallic Complexes Containing Conjugated and Aromatic Hydrocarbons as Bridging Ligands,"
Organometallics 1988, 7, 665-669.

31. S. C. Shah, J. S. Johnson, H. M. Brothers II, and N. M. Kostić,
"Covalent Modification of Cytochrome c with a Chelate Hydrazone Complex of Platinum(II),"
J. Serb. Chem. Soc. 1988, 53, 139-148.

32. L. Zhu, L. M. Daniels, L. M. Peerey, and N. M.Kostić
"A New Synthesis and Molecular Structure of Diferrocenylmercury Monohydrate,"
Acta Crystallogr., Sect. C. 1988, C44, 1727-1729.

33. J. Chen and N. M. Kostić,
"Binuclear Transition-Metal Complexes as New Reagents for Selective Cross­Linking of Proteins. Coordination of Cytochrome c to Dirhodium(II)-m-tetraacetate,"
Inorg. Chem. 1988, 27, 2682-2687.

34. E. M. A. Ratilla and N. M.Kostić,
"Guanidyl Groups—New Metal-Binding Ligands in Biomolecules. Reactions of Chloro(2,2':6':,2"-terpyridine)platinum(II) with Arginine in Cytochrome c and with Other Guanidyl Ligands,"
J. Am. Chem. Soc. 1988, 110, 4427-4428.

35. X.-Y. Zhou and N. M. Kostić,
"Concurrent and Reversible Changes of Color and of Phase in Aqueous Solution of (2,6­Pyridinedicarboxylato)chloroplatinate(II) Complex. Crystallographic Studies of the Discrete Monomer and of the Stacked Polymer,"
Inorg. Chem. 1988, 27, 4402-4408.

36. N. M. Kostić,
"Selective Labeling, Cross-Linking, and Cleavage of Proteins with Transition-Metal Complexes,"
Comments Inorg. Chem. 1988, 8, 137-162.

37. L. M. Peerey and N. M.Kostić,
"Oxido-Reduction Reactions Involving the Electrostatic and the Covalent Complex of Cytochrome c and Plastocyanin. Importance of the Protein Rearrangement for the Intracomplex Electron-Transfer Reaction,"
Biochemistry 1989, 28, 1861-1868.

38. E. M. A. Ratilla, B. K. Scott, M. S. Moxness, and N. M. Kostić,
"Terminal and New Bridging Coordination of Methylguanidine, Arginine, and Canavanine to Platinum(II). The First Crystallographic Study of Bonding Between a Transition Metal and a Guanidine Ligand,"
Inorg. Chem. 1990, 29, 918-926.

39. X. Y. Zhou and N. M. Kostić
"Steric Effects on the Selectivity of Protein labeling with Chelate Complexes of Platinum(II),"
Polyhedron 1990, 9, 1975-1983.

40. H. M. Brothers II and N. M. Kostić
"Catalytic Activity of the Serine Proteases a-Chymotrypsin and a-Lytic Protease Tagged at the Active Site with a (Terpyridine)platinum(II) Chromophore,"
Biochemistry 1990, 29, 7468-7474.

41. N. M. Kostić
"Diprotein Complexes and Their Electron-Transfer Reactions,"
Metal Ions in Biological Systems 1991, 27, 129-182.

42. J. S. Zhou and N. M. Kostić
"Kinetics of Static and Diffusive Electron Transfer between Zinc-Substituted Cytochrome c and Plastocyanin. Indications of Nonelectrostatic Interactions between Highly-Charged Metalloproteins,"
J. Am. Chem. Soc. 1991, 113, 6067-6073.

43. L. M. Peerey, H. M. Brothers II, J. T. Hazzard, G. Tollin, and N. M. Kostić
"Unimolecular and Bimolecular Oxidoreduction Reactions Involving Diprotein Complexes of Cytochrome c and Plastocyanin. Dependence of Electron-Transfer Reactivity on Charge and Orientation of the Docked Metalloproteins,"
Biochemistry 1991, 30, 9297-9304.

44. J. S. Zhou and N. M. Kostić
"Reactions between Cytochrome c and Plastocyanin Indicate That Choice of Docking Sites on Protein Surfaces May Depend on Thermodynamic Driving Force for Electron Transfer,"
J. Am. Chem. Soc. 1991, 113, 7040-7042.

45. I. E. Burgeson and N. M. Kostić
"Selective Hydrolysis of Peptides Promoted by Platinum(II) Complexes Anchored to Amino-Acid Side Chains,"
Inorg. Chem. 1991, 30, 4299-4305.

46. S. L. Pinnow, H. M. Brothers II, and N. M. Kostić
"Selective Labeling of the Enzyme Papain with Chloro(terpyridine)platinum(II),"
Croat. Chim. Acta 1991, 64, 519-528.

47. L. Zhu, H. Wadepohl, and N. M,Kostić,
"Electronic Structure and Bonding in Cluster Molecules Containing Metal­Bridging Benzene,"
Chin. J. Inorg. Chem. 1992, 8, 1-6.

48. A. J. Lukes and N. M. Kostić,
"Disproportionation Involving an Organomercurial and a Sulfhydryl-containing Protein. Reaction between Chloromercuryferrocene and Bakers'­Yeast Cytochrome c,"
J. Inorg. Biochem. 1992, 46, 77-85.

49. L. Qin and N. M. Kostić,
"Electron­Transfer Reactions of Cytochrome f with Flavin Semiquinones and with Plastocyanin. Importance of Protein-Protein Electrostatic Interactions and of Donor­Acceptor Coupling,"
Biochemistry 1992, 31, 5145-5150.

50. J. S. Zhou, H. M. Brothers II, J. P. Neddersen, L. M. Peerey, T. M. Cotton, and N. M. Kostić,
"Metalloprotein Complexes for the Study of Electron­Transfer Reactions. Characterization of Diprotein Complexes Obtained by Covalent Cross­Linking of Cytochrome c and Plastocyanin with a Carbodiimide,"
Bioconjugate Chemistry 1992, 3, 382-390.

51. E. M. A. Ratilla and N. M. Kostić,
"Photoreduction and Photoinduced Autoreduction of Ferricytochrome c,"
J. Serb. Chem. Soc. 1992, 57, 205-215.

52. J. S. Zhou and N. M. Kostić,
"Photoinduced Electron Transfer from Zinc Cytochrome c to Plastocyanin is Gated by Surface Diffusion Within the Metalloprotein Complex,"
J. Am. Chem. Soc. 1992, 114, 3562-3563.

53. J. S. Zhou and N. M.Kostić,
"Photoinduced Electron-Transfer Reaction in a Ternary System Involving Zinc Cytochrome c and Plastocyanin. Interplay of Monopolar and Dipolar Electrostatic Interactions Between Metalloproteins,"
Biochemistry 1992, 31, 7543-7550.

54. J. S. Zhou and N. M. Kostić,
"Zinc Cytochrome c as a Photochemical Probe for Studying Electron-Transfer Reactions in Metalloprotein Complexes,"
The Spectrum 1992, 5, No. 2, 1-6.

55. L. Zhu and N. M. Kostić,
"Toward Artificial Metallopeptidases—Mechanisms by Which Platinum(II) and Palladium(II) Complexes Promote Selective, Fast Hydrolysis of Unactivated Amide Bonds in Peptides,"
Inorg. Chem. 1992, 31, 3994-4001.

56. N. M. Kostić,
"Transition-Metal Complexes as Spectroscopic Probes for Selective Covalent Labeling and Cross-Linking of Proteins,"
Methods in Enzymology 1993, 226, 565-576.

57. H. M. Brothers, II, J. S. Zhou, and N. M. Kostić,
"Protein-Protein Orientation in Electron-Transfer Reactions of the Cytochrome c/Plastocyanin Complex with Free Cytochrome c and with Free Plastocyanin,"
J. Inorg. Organomet. Polymers 1993, 3, 59-76.

58. E. M. Lempers, J. S. Bashkin, and N. M. Kostić,
"A New Trinuclear Complex of Platinum and Iron Efficiently Promotes Cleavage of Plasmid DNA,"
Nucl. Acid Res. 1993, 21, 1983-1990.

59. J. S. Zhou and N. M. Kostić,
"Comparison of Electrostatic Interactions and of Protein-Protein Orientations in Electron­Transfer Reactions of Plastocyanin with the Triplet State of Zinc Cytochrome c and with Zinc Cytochrome c Cation Radical,"
Biochemistry 1993, 32, 4539-4546.

60. L. Zhu and N. M. Kostić
"Selective Hydrolysis of Peptides, Promoted by Palladium Aqua Complexes. Kinetic Effects of the Leaving group, pH, and Inhibitors,"
J. Am. Chem. Soc. 1993, 115, 4566-4570.

61. L. Qin and N. M. Kostić,
"Importance of Protein Rearrangement in the Electron-Transfer Reaction between the Physiological Partners Cytochrome f and Plastocyanin,"
Biochemistry 1993, 32, 6073-6080.

62. J. S. Zhou and N. M. Kostić,
"Gating of Photoinduced Electron Transfer from Zinc Cytochrome c and Tin Cytochrome c to Plastocyanin. Effects of Solution Viscosity on Rearrangement of the Metalloprotein Complex,"
J. Am. Chem. Soc. 1993, 115, 10796-10804.

63. L. Zhu, L. Qin, T. N. Parac, and N. M. Kostić,
"Site-Specific Hydrolytic Cleavage of Cytochrome c and of its Heme Undecapeptide, Promoted by Coordination Complexes of Palladium(II),"
J. Am. Chem. Soc. 1994, 116, 5218-5224.

64. J. Cheng, J. S. Zhou, and N. M.Kostić,
"Photoinduced Electron-Transfer Reactions of Plastocyanin with the Triplet State of Zinc Myoglobin and with Zinc Myoglobin Cation Radical. Importance of Electrostatic Interactions for Protein-Protein Orientation,"
Inorg. Chem., 1994, 33, 1600-1606.

65. L. Zhu and N. M.Kostić,
"Hydrolytic Cleavage of Peptides by Palladium(II) Complexes is Enhanced as Coordination of Peptide Nitrogen to Palladium(II) is Suppressed,"
Inorg. Chim. Acta, 1994, 217, 21-28.

66. L. Qin and N. M. Kostić,
"Photoinduced Electron Transfer from the Triplet State of Zinc Cytochrome c to Ferricytochrome b5 Is Gated by Configurational Fluctuations of the Diprotein Complex,"
Biochemistry 1994, 33, 12592-12599.

67. G. M. Ullmann and N. M. Kostić,
"Electron-Tunneling Paths in Various Electrostatic Complexes Between Cytochrome c and Plastocyanin. Anisotropy of the Copper-Ligand Interactions and Dependence of the Iron-Copper Electronic Coupling on the Metalloprotein Orientation,"
J. Am. Chem. Soc. 1995, 117, 4766-4774.

68. N. Juranić, V. Likić, N. M. Kostić, and S. Macura,
"Conformation of S-Glutathionato(2,2':6',2"-terpyridine)platinum(II) Ion, [Pt(trpy)GS]+, Determined from Cross-Relaxation Effects in Two-Dimensional 1H NMR Spectra. Importance of Ligand-Ligand Hydrophobic Interactions in Metal-Peptide Complexes,"
Inorg. Chem. 1995, 34, 938-944.

69. T. N. Parac and N. M.Kostić,
"New Selectivity and Turnover in Peptide Hydrolysis by Metal Complexes. A Palladium(II) Aqua Complex Catalyzes Cleavage of Peptides Next to the Histidine Residue,"
J. Am. Chem. Soc. 1996, 118, 51-58.

70. N. M. Kostić,
"Covalent Modification and Cross-Linking of Cytochrome c with Metal Complexes," Chapter 18
In “Cytochrome c: A Multidisciplinary Approach,” edited by A. G. Mauk and R. A. Scott,
University Science Books, 1996.

71. E. N. Korneeva, M. V. Ovchinnikov, and N. M.Kostić,
"Peptide Hydrolysis Promoted by Polynuclear and Organometallic Complexes of Palladium(II) and Platinum(II),"
Inorg. Chim. Acta 1996, 243, 9-13.

72. N. M.Kostić,
"Dynamic Aspects of Electron-Transfer Reactions in Metalloprotein Complexes," Chapter In “Metal-Containing Polymeric Mateerials,” edited by C. U. Pittman, Jr., et al., Plenum Publishing Co., 1996.

73. L. Qin and N. M.Kostić,
"Enforced Interaction of one Molecule of Plastocyanin with Two Molecules of Cytochrome c and an Electron-Transfer Reaction Involving the Hydrophobic Patch on the Plastocyanin Surface,"
Biochemistry 1996, 35, 3379-3386.

74. C. Shen and N. M.Kostić,
"Reductive Quenching of the Triplet State of Zinc Cytochrome c by Hexacyanoferrate(II) Ion and by Ethylenediaminetetraacetic Acid,"
Inorg. Chem. 1996, 35, 2780-2784.

75. X. Chen, L. Zhu, H. Yan, X. You, and N. M.Kostić,
"Kinetic Study of Stereochemical and Other Factors Governing Hydrolytic Cleavage of a Peptide Ligand in Binuclear Palladium(II) Complexes,"
J. Chem. Soc., Dalton Trans. 1996, 2653-2658.

76. T. N. Parac and N. M.Kostić,
"Effects of Linkage Isomerism and of Acid-Base Equilibria on Reactivity and Catalytic Turnover in Hydrolytic Cleavage of Histidyl Peptides Coordinated to Palladium(II). Identification of the Active Complex between Palladium(II) and the Histidyl Residue."
J. Am. Chem. Soc. 1996, 118, 5946-5951.

77. X. Chen, L. Zhu, H. Yan, N. M.Kostić, and X. You,
"Kinetic Study of the Reaction of cis-[Pd(en)(H2O)2](NO3)2 and N-AcCysMe,"
Chinese Sci. Bull. 1996, 41, 390-394.

78. N. V. Kaminskaia and N. M. Kostić,
"Nitrile Hydration Catalyzed by Palladium(II) Complexes,"
J. Chem. Soc., Dalton Trans. 1996, 3677-3686.

79. M. and N. M. Kostić,
"Effects of Temperature on the Kinetics of the Gated Electron-Transfer Reaction Between Zinc Cytochrome c and Plastocyanin. Analysis of Configurational Fluctuation of the Diprotein Complex,"
Biochemistry 1996, 35, 15095-15106.

80. X. Chen, L. Zhu, and N. M. Kostić,
"Hydrolytic Cleavage of AcMet-Gly Promoted by cis-[Pd(Met)(H2O)2](NO3)2,"
Chin. Chem. Lett. 1996, 7, 127-128.

81. M. M. Crnogorac, C. Shen, S. Young, Ö. Hansson, and N. M.Kostić,
"Effects of Mutations in Plastocyanin on the Kinetics of the Protein Rearrangement Gating the Electron-Transfer Reaction with Zinc Cytochrome c. Analysis of the Rearrangement Pathway,"
Biochemistry 1996, 35, 16465-16474.

82. G. M. Ullmann, E.-W. Knapp, and N. M.Kostić,
"Computational Simulation and Analysis of Dynamic Association between Plastocyanin and Cytochrome f. Consequences for the Electron-Transfer Reaction,"
J. Am. Chem. Soc. 1997, 119, 42-52.

83. S. Ye, C. Shen, T. M. Cotton, and N. M.Kostić,
“Characterization of Zinc-Substituted Cytochrome c by Circular Dichroism and Resonance Raman Spectroscopic Methods”
J. Inorg. Biochem. 1997, 65, 219-226.

84. C. Shen and N. M.Kostić,
"Kinetics of Photoinduced Electron-Transfer Reactions within Sol-Gel Silica Glass Doped with Zinc Cytochrome c. Study of Electrostatic Effects in Confined Liquids,"
J. Am. Chem. Soc. 1997, 119, 1304-1312.

85. C. Shen and N. M. Kostić,
"Photoinduced Electron Transfer from Zinc Cytochrome c to Cationic Ruthenium(III) Complexes within Silica Glass Prepared by the Sol-Gel Method,"
J. Electroanal. Chem. 1997, 438, 61-65.

86. M. M. and N. M. Kostić,
"Effects of Viscosity and Temperature on the Kinetics of the Gated Electron-Transfer Reaction between the Triplet State of Zinc Cytochrome c and Cupriplastocyanin,"
Biochemistry 1997, 36, 8135-8144.

87. S. U. T. N. Parac, M. I. Djuran, and N. M. Kostić,
"Dependence of Hydrolytic Cleavage of Histidine-Containing Peptides by Palladium(II) Aqua Complexes on the Coordination Modes of the Peptides,"
J. Chem. Soc., Dalton Trans. 1997, 2771-2776.

88. T. N. Parac and N. M.Kostić,
"Compounds Analogous to Intermediates in Hydrolytic Cleavage of Peptides by Palladium(II) Complexes,"
J. Serb. Chem. Soc. 1997, 62, 847-855

89. N. V. Kaminskaia and N. M. Kostić,
"Kinetics and Mechanism of Urea Hydrolysis Catalyzed by Palladium(II) Complexes,"
Inorg. Chem. 1997, 36, 5917-5926.

90. G. M. Ullmann, M. Hauswald, A. Jensen, N. M.Kostić, and E.-W. Knapp,
"Comparison of Physiologically-Equivalent Proteins Cytochrome c6 and Plastocyanin on the Basis of Their Electrostatic Potentials. Tryptophane 63 in Cytochrome c6 May be Isofunctional with Tyrosine 83 in Plastocyanin,"
Biochemistry 1997, 36, 16187-16196.

91. X. Chen, L. Zhu, and N. M.Kostić,
"Steric Effects, Solvent Effects, and Turnover in Hydrolytic Cleavage of Peptides Promoted by Palladium(II) Aqua Complexes,"
J. Biol. Inorg. Chem. 1998, 3, 1-8.

92. T. N. Parac and N. M.Kostić,
"Regioselective Cleavage by a Palladium(II) Aqua Complex of a Polypeptide in Different Overall Conformations,"
Inorg. Chem. 1998, 37, 2141-2144.

93. G. B. Karet and N. M.Kostić,
"Rapid, Catalytic Hydrolysis of Methionine-Containing Dipeptides by a Dinuclear Palladium(II) Complex Having Thiolate Bridging Ligands,"
Inorg. Chem. 1998, 37, 1021-1027.

94. X. Chen, L. Zhu, and N. M.Kostić,
"A Tetranuclear Complex of Palladium(II) with Cysteine,"
Acta Crystallogr. Sect. C. 1998, 54, 909-911.

95.  L. Zhu, R. Bakhtiar, and N. M. Kostić,
"Transition-Metal Complexes as Alternatives to Proteolytic Enzymes. Regioselective Cleavage of Myoglobin by Palladium(II) Aqua Complexes,"
J. Biol. Inorg. Chem. 1998, 3, 383-391.

96. N. V. Kaminskaia and N. M.Kostić,
"Alcoholysis of Urea Catalyzed by Palladium(II) Complexes,"
Inorg. Chem. 1998, 37, 4302-4312.

97. M. M. G. M. Ullmann, S. Young, Ö. Hansson, M. M. Crnogorac, M. Ejdebäck, and N. M.Kostić,
"Effects of Single and Double Mutations in Plastocyanin on the Rate Constant and Activation Parameters for the Rearrangement Gating the Electron-Transfer Reaction between the Triplet State of Zinc Cytochrome c and Cupriplastocyanin,"
Biochemistry 1998, 37, 9557-9569.

98. N. V. Kaminskaia, I. A. Guzei, and N. M.Kostić,
"Interplay between the Palladium(II) Ion, Unidentate Ligands, and Hydroxyl Groups from a Bidentate Ligand in a New Complex That Catalyzed Hydration and Alcoholysis of Nitrile and Urea,"
J. Chem. Soc., Dalton Trans. 1998, 3879-3885.

99. T. N. Parac, G. M. Ullmann, and N. M.Kostić,
"New Regioselectivity in the Cleavage of Histidine–Containing Peptides by Palladium(II) Complexes Studied by Kinetic Experiments and Molecular Dynamics Simulations,"
J. Am. Chem. Soc. 1999, 121, 3127-3135.

100. M. M. G. M. Ullmann, M. M. Crnogorac, M. Ejdebäck, S. Young, Ö. Hansson, and N. M. Kostić,
"Comparing the Rates and the Activation Parameters for the Forward Reaction between the Triplet State of Zinc Cytochrome c and Cupriplastocyanin and the Back Reaction between the Zinc Cytochrome c Cation Radical and Cuproplastocyanin,"
Biochemistry 1999, 38, 1589-1597.

101. E. V. Sokerina, G. M. Ullmann, G. van Pouderoyen, G. W. Canters, and N. M. Kostić,
“Electrostatic Effects on the Kinetics of Photoinduced Electron-Transfer Reactions of the Triplet State of Zinc Cytochrome c with Wild-Type and Mutant Forms of Pseudomonas aeruginosa Azurin,”
J. Biol. Inorg. Chem. 1999, 4, 111-121.

102. K. Olesen, M. Ejdebäck, M. M. Crnogorac, N. M. Kostić, and Ö. Hansson,
“Electron Transfer to Photosystem 1 from Spinach Plastocyanin Mutated in the Small Acidic Patch: Ionic Strength Dependence of Kinetics and Comparison of Mechanistic Models,”
Biochemistry 1999, 38, 16695-16705.

103. N. V. Kaminskaia, T. W. Johnson, and N. M. Kostić,
“Regioselective Hydrolysis of Tryptophan-Containing Peptides Promoted by Palladium(II) Complexes,”
J. Am. Chem. Soc. 1999, 121, 8663-8664.

104. J. D. Badjić and N. M. Kostić,
“Effects of Encapulation in Sol-Gel Silica Glass on Esterase Activity, Conformational Stability, and Unfolding of Bovine Carbonic Anhydrase II,”
Chem. Mater. 1999, 11, 3671-3679.

105. M. M. Crnogorac and N. M. Kostić,
“Redox Reactivity and Reorganization Energy of Zinc Cytochrome c Cation Radical,”
Inorg. Chem. 2000, 39, 5028-5035.

106. E. V. Pletneva, D. B. Fulton, T. Kohzuma, and N. M. Kostić,
“Protein Docking and Gated Electron-Transfer Reactions between Zinc Cytochrome c and the New Plastocyanin from the Fern Dryopteris crassirhizoma. Direct Kinetic Evidence for Multiple Binary Complexes,”
J. Am. Chem. Soc. 2000, 122, 1034-1046.

107. S. M. Tremain and N. M. Kostić,
“Fate of the Excited Triplet State of Zinc Cytochrome c in the Presence of Iron(III), Iron(II), Iron-Free, and Heme-Free Forms of Cytochrome c,”
Inorg. Chim. Acta 2000, 300-302, 733-740.

108. N. V. Kaminskaia, G. M. Ullmann, D. B. Fulton, and N. M. Kostić,
“Spectroscopic, Kinetic, and Mechanistic Study of a New Mode of Coordination of Indole Derivatives to Platinum(II) and Palladium(II) Ions in Complexes,”
Inorg. Chem. 2000, 39, 5004-5013.

109. J. D. Badjić and N. M. Kostić,
“Unexpected Interactions between Sol-Gel Silica Glass and Guest Molecules. Extraction of Aromatic Hydrocarbons into Polar Silica from Hydrophobic Solvents,”
J. Phys. Chem. B 2000, 104, 11081-11087.

110. N. M. Milović and N. M. Kostić,
“Selective Cleavage of Peptide Bonds by Palladium(II) and Platinum(II) Complexes,”
In Metal Ions in Biological Systems; A. Sigel and H. Sigel, Eds.; Marcel Dekker: New York, 2001; Vol. 38, pp 145-186.

111. E. N. Kadnikova and N. M. Kostić,
“Sol-Gel Glass is Not Necessarily an Inert Matrix for Enzyme Encapsulation. Catalysis of Sulfoxidation by Silica,”
J. Non-Cryst. Solids 2001, 283, 63-68.

112. J. D. Badjić and N. M. Kostić,
“Behavior of Organic Compounds Confined in Monoliths of Sol-Gel Silica Glass. Effects of Guest-Host Hydrogen Bonding on Uptake, Release, and Isomerization of the Guest Compounds,”
J. Mater. Chem. 2001, 11, 408-418.

113. M. M. Crnogorac, G. M. Ullmann, and N. M. Kostić,
“Effects of pH on Protein Association: Modification of the Proton-Linkage Model and Experimental Verification of the Modified Model in the Case of Cytochrome c and Plastocyanin,”
J. Am. Chem. Soc. 2001, 123, 10789-10798.

114. N. V. Kaminskaia and N. M. Kostić,
“Acetoxime Coordinates to Palladium(II) and is Catalytically Hydrolysed to Acetone,”
J. Chem. Soc., Dalton Trans. 2001, 1083-1086.

115. N. V. Kaminskaia and N. M. Kostić,
“New Selectivity in Peptide Hydrolysis by Metal Complexes. Platinum(II) Complexes Promote Cleavage of Peptides Next to the Tryptophan Residue,”
Inorg. Chem. 2001, 40, 2368-2377.

116. E. V. Pletneva, A. T. Laederach, D. B. Fulton, and N. M. Kostić,
“The Role of Cation-p Interactions in Biomolecular Association. Design of Peptides Favoring Interactions between Cationic and Aromatic Amino-Acid Side Chains,”
J. Am. Chem. Soc. 2001, 123, 6232-6245.

117. J. D. Badjić and N. M. Kostić,
“Reactivity of Organic Compounds Inside Micelles Embedded in Sol-Gel Glass. Kinetics of Isomerization of Azobenzene Inside CTAB and SDS Micelles,”
J. Phys. Chem. B 2001, 105, 7482-7489.

118. J. D. Badjić, E. N. Kadnikova, and N. M. Kostić,
“Enantioselective Aminolysis of a­Chloroester Catalyzed by Candida cylindracea Lipase Encapsulated in Sol-Gel Glass,”
Org. Lett. 2001, 3, 2025-2028.

119. S. M. Tremain and N. M. Kostić,
“Molten-Globule and Other Conformational Forms of Zinc Cytochrome c. Effect of Partial and Complete Unfolding of the Protein on its Electron-Transfer Reactivity,”
Inorg. Chem. 2002, 41, 3291-3301.

120. L. Zhu, A. M. Ellern, and N. M. Kostić,
“The Binary Adduct of 3, 6, 9, 16, 19, 22-Hexaazatricyclo[22.2.2.211,14] Triaconta-11,13,24,26(1), 27, 29-Hexaene and Benzene-1, 2, 4, 5-tetracarboxylic Acid Hexahydrate,”
Acta Cryst. 2002, C58, 0129-0130.

121. E. N. Kadnikova and N. M. Kostić,
“Oxidation of ABTS by Hydrogen Peroxide Catalyzed by Horseradish Peroxidase Encapsulated into Sol-Gel Glass. Effects of Glass Matrix on Reactivity,”
J. Mol. Catal. B: Enzymatic 2002, 18, 39-48.

122. N. M. Milović and N. M. Kostić,
“Palladium(II) Complexes, as Synthetic Peptidases, Regioselectively Cleave the Second Peptide Bond “Upstream” from Methionine and Histidine Side Chains,”
J. Am. Chem. Soc. 2002, 124, 4759-4769.

123. L. Zhu and N. M. Kostic´ ,
“Sequence-Dependent Cleavage of Albumin with Palladium(II) Complexes: Role of Serine Residue in Controlling the High Regioselectivity of Protein Cleavage,”
Inorg. Chim. Acta 2002, 339, 104-110.

124. E. V. Pletneva, M. M. Crnogorac, and N. M. Kostic´ ,
“Mimicking Biological Electron Transport in Sol-Gel Glass: Photoinduced Electron Transfer from Zinc Cytochrome c to Plastocyanin or Cytochrome c Mediated by Mobile Inorganic Complexes,”
J. Am. Chem. Soc. 2002, 124, 14342-14354.

125. N. M. Milović and N. M. Kostić,
“Interplay of Terminal Amino Group and Coordinating Side Chains in Directing Regioselective Cleavage of Natural Peptides and Proteins with Palladium(II) Complexes,”
Inorg. Chem. 2002, 41, 7053-7063.

126. N. M. Milovic´ and N. M. Kostic´ ,
“Palladium (II) Complex as a Sequence-Specific Peptidase: Hydrolytic Cleavage Under Mild Conditions of X-Pro Peptide Bonds in X-Pro-Met and X-Pro-His Segments,”
J. Am. Chem. Soc. 2003, 125, 781-788.

127. E. N. Kadnikova and N. M. Kostić,
“Effects of the Environment on Microperoxidase-11 and on its Catalytic Activity in Oxidation of Organic Sulfides to Sulfoxides,”
J. Org. Chem. 2003, 68, 2600-2608.

128. M. M. Crnogorac and N. M. Kostic´ ,
“Effects of pH on Kinetics of the Structural Rearrangement that Gates the Electron-Transfer Reaction between Zinc Cytochrome c and Plastocyanin. Analysis of Protonation States in a Diprotein Complex,”
J. Serb. Chem. Soc. 2003, 68, 327-337.

129. N. M. Milovic´ , L. M. Dutca˘ , and N. M. Kostic´ ,
“Combined Use of Platinum(II) Complexes and Palladium(II) Complexes for Selective Cleavage of Peptides and Proteins,”
Inorg. Chem. 2003, 42, 4036-4045.

130. N. M. Milović, L. M. Dutca˘ , and N. M. Kostic´ ,
“Transition-Metal Complexes as Enzyme-like Reagents for Protein Cleavage: Complex cis-[Pt(en)(H2O)2]2+ as a New Methionine-Specific Protease,”
Chem.- Eur. J. 2003, 9, 5097-5106.

131. N. M. Kosti c´ and L. M. Dutca˘ ,
“Palladium,” chapter 6.4 in
Comprehensive Coordination Chemistry II, Vol. 6, 555-672;
Elsevier, 2003.

132. T. Zˇ . Grove and N. M. Kostic´ ,
“Metalloprotein Association, Self-association, and Dynamics Governed by Hydrophobic Interactions. Simultaneous Occurrence of Gated and True Electron-Transfer Reactions between Cytochrome f and Cytochrome c6 from Chlamydomonas reinhardtii,”
J. Am. Chem. Soc. 2003, 125, 10598-10607.

133. N. M. Milovic´ , J. D. Badjić, and N. M. Kostic´ ,
“Conjugate of Palladium(II) Complex and β-Cyclodextrin Acts as a Biomimetic Peptidase,”
J. Am. Chem. Soc. 2004, 126, 696-697.

134. T. W. Johnson and N. M. Kostić
“Steric Effects on the Rate of Hydrolysis by Palladium(II) Complexes of the C-terminal Amide Bonds in a Series of methionine-Containing Dipeptides acMet-Aa,”
J. Serb. Chem. Soc. 2004, 69, 887-899.

135. L.-M. Dutcă, K.-S. Ko, N. L. Pohl, and N. M. Kostić,
“Platinum(II) Complex as an Artificial Peptidase: Selective Cleavage of Peptides and a Protein by cis-[Pt(en)(H2O)2]2+ Ion under Ultraviolet and Microwave Irradiation,”
Inorg. Chem. 2005, 44, 5141-5146.

136. I. Slowing, W. Luo, M. Hong, and N. M. Kostić,                
“New Method for Tight Encapsulation of Proteins in Silica, With the Proteins Serving as Catalytic Templates for Silica Polymerization. Dependence of Lactate Dehydrogenase Activity on Conformational Constriction of the Enzyme by the Silica Matrix,” 
submitted for publication.

137. C. Shen and N. M. Kostić,
“Reactivity of Molecules Confined Within Pores of Sol-Gel Silica Glass. Kinetics of Photoinduced Electron Transfer from Zinc Cytochrome c to Hexaammineruthenium(III) Cation,”
submitted for publication.

138. S. A. Stoffregen, A. K. K. Griffin, and N. M. Kostić,
“Thioether Complexes of Palladium(II) and Platinum(II) as Artificial Peptidases. Residue-Selective and Sequence-Selective Peptide Cleavage by a Palladium(II) Complex,”
Inorg. Chem. 2005, 44, 8899-8907.

139. T. Ž. Grove, G. M. Ullmann, and N. M. Kostić,
“Simultaneous True, Gated, and Coupled Electron-Transfer Reactions and Energetics of Protein Rearrangement,”
submitted for publication.

140. C. Shen and N. M. Kostić,
“Reactivity of Proteins and Small Molecules Confined Within Pores of Sol-Gel Silica Glass. Kinetics of Photoinduced Electron Transfer from Zinc Myoglobinto Anionic and Electroneutral Quenchers,”
submitted for publication.

141. J. A. Crank and N. M. Kostić,
“Protein-Doped Glasses Prepared by the Sol-Gel Method as Monolithic Stationary Phases for Use in Capillary Affinity Chromatography,”
submitted for publication.

 

Manuscripts in Preparation

Research for these papers is complete, and findings have been reported at meetings and in invited seminars.

143. M. Suh, E. M. A. Ratilla, and N. M.
“Binding to DNA of the Double­Decker Complex, [{Pt(trpy)}2Can]3+, a Nonintercalator that Gives Signs of Intercalation.”

144. G. B. Karet and N. M.
“Mechanism of Hydrolytic Cleavage of Peptides Catalyzed by Dinuclear Palladium(II) Complexes.”

145. G. B. Karet and N. M.
“Fast, Hydrolytic Cleavage of Methionine-Containing Peptides by Platinum(II) Complexes.”